| Identification | Back Directory | [Name]
fosaprepitant dibenzyl ester | [CAS]
265121-01-5 | [Synonyms]
Fosaprepitant Impurity R
Fosaprepitant Impurity Q
fosaprepitant dibenzyl ester
Fosaprepitant Dimeglumine Dibenzylester Impurity
dibenzyl(3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate
Dibenzyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-4-ethyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate
Phosphonic acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, bis(phenylmethyl) ester | [Molecular Formula]
C37 H34 F7 N4 O6 P | [MOL File]
265121-01-5.mol | [Molecular Weight]
794.65 |
| Chemical Properties | Back Directory | [Melting point ]
>50°C (dec.) | [density ]
1.42±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.07±0.20(Predicted) | [color ]
White to Light Yellow | [Stability:]
Moisture Sensitive |
| Hazard Information | Back Directory | [Uses]
Fosaprepitant Dibenzyl Ester is a reactant in the synthetic preparation of phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water soluble prodrugs. |
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