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ChemicalBook--->CAS DataBase List--->2578-57-6

2578-57-6

2578-57-6 Structure

2578-57-6 Structure
IdentificationBack Directory
[Name]

H-PRO-GLY-OH
[CAS]

2578-57-6
[Synonyms]

PRO-GLY
L-PRO-GLN
H-PRO-GLY-OH
prolylglycine
N-prolylglycine
L-PROLYLGLYCINE
Glycine, L-prolyl-
PRO-GLY MONOHYDRATE
H-PRO-GLY-OH USP/EP/BP
Pro-Gly-OH≥ 95% (HPLC)
Glycine, L-prolyl- (9CI)
2-(prolylamino)acetic acid
2-(pyrrolidine-2-carbonylamino)acetic acid
(S)-2-(pyrrolidine-2-carboxaMido)acetic acid
2-(pyrrolidin-2-ylcarbonylamino)ethanoic acid
2-{[(2S)-pyrrolidin-2-yl]formamido}acetic acid
[Molecular Formula]

C7H12N2O3
[MDL Number]

MFCD00022391
[MOL File]

2578-57-6.mol
[Molecular Weight]

172.18
Chemical PropertiesBack Directory
[Melting point ]

236℃
[Boiling point ]

468.5±45.0 °C(Predicted)
[density ]

1.266±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

3.51±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

Substrate for prolinase (prolyl dipeptidase).
[Definition]

ChEBI: A dipeptide consisting of glycine having an L-prolyl group attached to its alpha-amino nitrogen.
[Biological Activity]

PRO-GLY is a dipeptide th at has previously been shown to prevent progression of diabetes.
[Purification Methods]

Recrystallise L-prolylglycine from water at 50-60o by addition of EtOH. [Appel et al. Chem Ber 108 2680 1975, Rydon & Smith J Chem Soc 3642 1956.]
Spectrum DetailBack Directory
[Spectrum Detail]

H-PRO-GLY-OH(2578-57-6)13CNMR
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