Identification | Back Directory | [Name]
CP-456773 sodium | [CAS]
256373-96-3 | [Synonyms]
CPD1600 Crid3 sodium MCC950 sodium CP-456773 sodium MCC950(CP-456773) CRID3 sodium salt MCC 950 sodium NEW MCC950 sodium salt CP-456773 sodium salt MCC-950 Sodium, CP-456773 MCC950 (CP-456773) sodium MCC950 Sodium Salt (CP-456773) MCC950 sodium (CP-456773 sodium CP-456773 sodium salt >=98% (HPLC) CP-456773 SODIUM; CRID3 SODIUM SALT; MCC-950 SODIUM; CP456773 SODIUM; CRID-3 SODIUM SALT sodium salt of 1-(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]-urea N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide monosodium salt | [Molecular Formula]
C20H23N2NaO5S | [MDL Number]
MFCD28580120 | [MOL File]
256373-96-3.mol | [Molecular Weight]
426.462 |
Chemical Properties | Back Directory | [storage temp. ]
room temp | [solubility ]
Soluble in DMSO:50.0(Max Conc. mg/mL);117.24(Max Conc. mM) Water:30.0(Max Conc. mg/mL);70.35(Max Conc. mM) | [form ]
powder | [color ]
white to beige |
Hazard Information | Back Directory | [Uses]
CP-456773 sodium salt has been used :
- In in vivo experiments to study the neuroprotective action of ketogenic diet.
- To study the effect of inhibition of NLRP3 (nod-like receptor protein 3) inflammasome activity on tumor progression in mouse models.
- To study the cholesterol crystal-mediated IL-1b (interleukin-1b) response in placental explants.
| [Biochem/physiol Actions]
CP-456773 is known to inhibit the release of other proinflammatory cytokines such as IL-1α and IL-18. It is also referred to as MCC950. | [storage]
+4°C |
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