| Identification | Back Directory | [Name]
5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE | [CAS]
252742-72-6 | [Synonyms]
-5(4H)-one
Aprepitant Impurity 51
3-Chloromethyl-1,2,4-triazol-5-one
3-Chloromethyl-1,2,4-triazolin-5-one
5-Chloromethyl-1H-[1,2,4]triazol-3-ol
5-(Chloromethyl)-4h-1,2,4-triazol-3-ol
5-ChloroMethyl-2H-1,2,4-triazolin-3-one
3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one
(chloromethyl)-1,2-dihydro-1,2,4-triazol-3-one
5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE
5-Chloromethyl-2,4-Dithydro-[1,2,4]Triazol-3-One
5-(chloromethyl)-1,2-dihydro-1,2,4-triazol-3-one
5-(chloromethyl)-1,2-dihydro-3H-1,2,4-Triazol-3-one
3-(chloroMethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
5-(CHLOORMETHYL)-1,2-DIHYDRO-3H-1,2,4-TRIAZOOL-3-ON
5-(chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
Aprepitant int-2 3-chloromethyl-1,2,4-triazolin-5-one
3H-1,2,4-Triazol-3-one, 5-(chloromethyl)-1,2-dihydro-
3-Chloromethyl-1,2,4-triazolin-5-one,Aprepitant intermediate
Aprepitant intermediates，5-Chloromethyl-2,4-dihydro-〔1,2,4〕 triazol-3-one
3-Chloromethyl-1,2,4-triazolin-5-one
5-Chloromethyl-2,4-dihydro-[1,2,4]triazol-3-one | [EINECS(EC#)]
607-678-2 | [Molecular Formula]
C3H4ClN3O | [MDL Number]
MFCD07776630 | [MOL File]
252742-72-6.mol | [Molecular Weight]
133.54 |
| Chemical Properties | Back Directory | [Melting point ]
199°C(lit.) | [density ]
1.83±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
7.46±0.20(Predicted) | [color ]
White to Almost white | [CAS DataBase Reference]
252742-72-6 |
| Hazard Information | Back Directory | [Chemical Properties]
White to Almost white powder to crystal | [Uses]
5-Chloromethyl-2H-1,2,4-triazolin-3-one(252742-72-6) is an intermediate used in the synthesis of Aprepitant (A729800) and
Fosaprepitant, used as antiemetic drugs.
| [Application]
3-Chloromethyl-1,2,4-triazolin-5-one(252742-72-6) is an intermediate in organic synthesis and pharmaceutical intermediate, which can be used in laboratory R&D synthesis process and chemical biological R&D process.
| [Hazard]
5-Chloromethyl-2H-1,2,4-triazolin-3-one is a hazardous chemical that is corrosive to metals, irritating to the eyes and skin, and may cause respiratory irritation. |
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