| Identification | Back Directory | [Name]
POLY(N-ISOPROPYL ACRYLAMIDE) | [CAS]
25189-55-3 | [Synonyms]
PNIPAM
nipam polymer
POLY(N-ISOPROPYL ACRYLAMIDE)
N-ISO-PROPYLACRYLAMIDE POLYMER
Poly(N-isopropylacrylamide) (PNiPAM)
Poly(N-isopropylacrylamide) Mn ~40,000
poly(N-isopropylacrylamide) macromolecule
n-(1-methylethyl)-2-propenamidhomopolymer
poly(n-iso-propylacrylamide)(mw20000-25000)
N-(1-Methylethyl)-2-propenamide homopolymer
Poly(N-isopropylacrylaMide) Mw 20,000-40,000
2-Propenamide,N-(1-methylethyl)-,homopolymer
Poly(N-isopropylacrylamide) Mn 20,000-40,000
Poly(N-isopropylacrylamide) average Mn 30,000
2-Propenamid, N-(1-methylethyl)-, Homopolymer
POLY(N-ISOPROPYL ACRYLAMIDE) ISO 9001：2015 REACH
Poly(N-isopropylacrylaMide), carboxylic acid terMinated average Mn 10,000
Poly(N-isopropylacrylamide),NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM
2-Propenamide, N-(1-methylethyl)-, homopolymer n-(1-methylethyl)-2-propenamid homopolymer | [Molecular Formula]
C6H11NO | [MDL Number]
MFCD00284282 | [MOL File]
25189-55-3.mol | [Molecular Weight]
113.158 |
| Hazard Information | Back Directory | [Chemical Properties]
mp 96°C phase transitions at 32°C to insoluble phase | [Uses]
PolyNIPAM is a stimuli-responsive polymer. The low PDI means that the distribution of chain lengths is narrow which will typically lead to better reproducibility. This polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain. | [Uses]
Poly(N-iso-propyl acrylaMide) can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.
| [Definition]
ChEBI: An acrylic macromolecule, arising from poymerisation of N-isopropylamide. | [General Description]
Poly(N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer used in biomedical research applications. PNIPAM undergoes a reversible, lower critical solution temperature (LCST) phase transition when heated above 32 °C, transitioning from a soluble to an insoluble material. PNIPAM is also frequently crosslinked to yield hydrogels with reversible, thermal shrinking and swelling. Poly(N-isopropylacrylamide) is also readily functionalized and has been used as the hydrophilic block in the synthesis of thermoresponsive, amphiphilic block copolymers. Due to the similarity in temperature between the LCST of PNIPAM and the temperature of the human body, PNIPAM materials have been frequently utilized in tissue engineering and controlled drug delivery research applications. | [Solubility in organics]
Acetone, THF, water (cold) |
|
|