| Identification | Back Directory | [Name]
N3-CYCLOPROPYL-7-[[4-(1-METHYLETHYL)PHENYL]METHYL]-7H-PYRROLO[3,2-F]QUINAZOLINE-1,3-DIAMINE DIHYDROCHLORIDE | [CAS]
245520-69-8 | [Synonyms]
Sch 79797
SCH797972HCl
SCH 79797 dihydrochl
SCH 79797 DIHYDROCHLORIDE
N3-Cyclopropyl-7-(4-isopropylbenzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine
3-N-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine
7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine,N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-
N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diaminedihydrochloride
N3-CYCLOPROPYL-7-[[4-(1-METHYLETHYL)PHENYL]METHYL]-7H-PYRROLO[3,2-F]QUINAZOLINE-1,3-DIAMINE DIHYDROCHLORIDE | [Molecular Formula]
C23H25N5 | [MDL Number]
MFCD12910520 | [MOL File]
245520-69-8.mol | [Molecular Weight]
371.48 |
| Chemical Properties | Back Directory | [Boiling point ]
644.4±65.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO : 50 mg/mL (134.60 mM; Need ultrasonic) | [form ]
Solid | [pka]
8.73±0.40(Predicted) | [color ]
Light yellow to brown |
| Hazard Information | Back Directory | [Uses]
SCH 79797 Dihydrochloride is a selective PAR1 antagonist. | [Definition]
ChEBI: N3-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine is a member of quinazolines. | [Biological Activity]
Potent, selective non-peptide PAR 1 receptor antagonist (IC 50 = 70 nM). Inhibits haTRAP-induced- but not g-thrombin-, ADP- or collagen-induced human platelet aggregation. Also selectively blocks PAR 1 agonist- or thrombin-induced increases in cytosolic Ca 2+ in vascular smooth muscle cells. | [storage]
Store at -20°C |
|
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NORANA GROUP
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027-027-59209883 17386169806 |
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www.nornachem.com |
| Company Name: |
InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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