Identification | Back Directory | [Name]
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide | [CAS]
24522-30-3 | [Synonyms]
Leflunomide Impurity H Leflunomide EP Impurity H 2-Cyano-N-[4-(trifluoromethyl)pheny 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide AcetaMide, 2-cyano-N-[4-(trifluoroMethyl)phenyl]- Leflunomide Impurity 8(Leflunomide EP Impurity H) 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide USP/EP/BP | [Molecular Formula]
C10H7F3N2O | [MDL Number]
MFCD05669245 | [MOL File]
24522-30-3.mol | [Molecular Weight]
228.18 |
Chemical Properties | Back Directory | [Melting point ]
145-147℃ | [Boiling point ]
386.3±42.0 °C(Predicted) | [density ]
1.375±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.63±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Uses]
2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide (Leflunomide EP Impurity H) is used to prepare aminothiophene carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. It is also used to synthesize (1,2,3-triazol-4-yl)benzenamines as inhibitors against VEGF receptors 1 and 2. |
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