Identification | Back Directory | [Name]
Methyltetrazine-PEG5-triethoxysilane | [CAS]
2353410-01-0 | [Synonyms]
Methyltetrazine-PEG5-triethoxysilane 1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-N-(3-(triethoxysilyl)propyl)-3,6,9,12-tetraoxapentadecan-15-amide | [Molecular Formula]
C29H49N5O9Si | [MDL Number]
MFCD31811540 | [MOL File]
2353410-01-0.mol | [Molecular Weight]
639.82 |
Hazard Information | Back Directory | [Description]
Methyltetrazine-PEG5-triethoxysilane is a click chemistry linker containing a triethoxysilane moiety and a methyltetrazine group. Triethoxysilane is commonly used for surface modifications. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The hydrophilic PEG chain increases the water solubility of a compound in aqueous media. |
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