| Identification | Back Directory | [Name]
MESO-2 3-DIAMINOSUCCINIC ACID | [CAS]
23220-52-2 | [Synonyms]
Einecs 245-500-1
erythro-3-aminoaspartic acid
(2R,3S)-diaminosuccinic acid
(3R)-3-Amino-L-aspartic acid
(2R,3S)-2,3-Diaminosuccinicaci
(2R,3S)-2,3-Diaminosuccinic acid
D-Aspartic acid, 3-amino-, (3S)-rel-
MESO-2 3-DIAMINOSUCCINIC ACID USP/EP/BP | [EINECS(EC#)]
245-500-1 | [Molecular Formula]
C4H8N2O4 | [MDL Number]
MFCD00037765 | [MOL File]
23220-52-2.mol | [Molecular Weight]
148.12 |
| Chemical Properties | Back Directory | [Melting point ]
304 °C | [Boiling point ]
304.7±42.0 °C(Predicted) | [density ]
1.611±0.06 g/cm3(Predicted) | [form ]
powder | [pka]
1.43±0.27(Predicted) |
| Hazard Information | Back Directory | [Uses]
meso-2,3-Diaminosuccinic Acid is used as a building block in organic synthesis. As well as used in the synthesis of metal complexes for antitumor activity. | [reaction suitability]
reaction type: solution phase peptide synthesis | [Purification Methods]
Crystallise the acid from water. Also, dissolve it in dilute NaOH and add AcOH to pH 5-6 and allow it to crystallise (m 304o dec). Alternatively dissolve the acid in aqueous NH3 and boil; when the NH3 has evaporated, the acid separates, filter it off and dry it at room temperature in a vacuum. In another procedure 1g of acid is dissolved in 10mL of conc HCl + 15mL of H2O at 80o, filter immediately, dilute with 20mL of H2O and allow to stand for 24hours. When the monohydrochloride (0.7g, m 175-156o dec) crystallises out, filter and dry it. It has also been purified by dissolving it in the minimum volume of 10% HCl, filtering, and diluting with 5volumes of H2O when the crystals separate slowly on standing. The acid is filtered off after 24hours and dried (m 306-306o dec). Similar procedures were used for the dl-isomer. [Kenner J Org Chem 13 28 1948, McKennis & Yard J Org Chem 23 980 1958, Beilstein 4 III 1528, 4 IV 3025.] |
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