| Identification | Back Directory | [Name]
BAY-6035 | [CAS]
2247890-13-5 | [Synonyms]
BAY-6035
1H-1,5-Benzodiazepine-7-carboxamide, 1-(3-azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-, (2S)- | [Molecular Formula]
C22H28N4O3 | [MDL Number]
MFCD31808259 | [MOL File]
2247890-13-5.mol | [Molecular Weight]
396.48 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:39.65(Max Conc. mg/mL);100.0(Max Conc. mM)
Ethanol:39.65(Max Conc. mg/mL);100.0(Max Conc. mM) | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
BAY 6035 is a potent and selective SMYD3 inhibitor. | [in vitro]
BAY-6035 specifically inhibited the methylation of MAP3K2 by SMYD3 in a cellular mechanistic assay with an IC50 <100 nM._x000D_
_x000D_
Reference: SLAS Discov. 2021 Jun 21:24725552211019409. https://journals.sagepub.com/doi/10.1177/24725552211019409?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed | [target]
BAY-6035 is a SMYD3 inhibitor. | [storage]
Store at -20°C |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://www.is0513.com/ShowSupplierProductsList927327/0.htm |
|