| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C, stored under nitrogen | [form ]
Solid | [color ]
White to off-white | [Water Solubility ]
Water : 56.67 mg/mL (76.74 mM; Need ultrasonic) |
| Hazard Information | Back Directory | [Biological Activity]
IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1].
IACS-8803 (10 μg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1]. | [storage]
Store at -20°C, stored under nitrogen | [References]
[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640. |
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| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
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