Identification | Back Directory | [Name]
Integracin B | [CAS]
224186-05-4 | [Synonyms]
Integracin B Benzoic acid, 2,4-dihydroxy-6-[(8R)-8-hydroxyundecyl]-, (1R)-8-(3,5-dihydroxyphenyl)-1-propyloctyl ester | [Molecular Formula]
C35H54O7 | [MOL File]
224186-05-4.mol | [Molecular Weight]
586.8 |
Chemical Properties | Back Directory | [Boiling point ]
759.5±59.0 °C(Predicted) | [density ]
1.114±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble; Methanol: soluble | [form ]
An oil | [pka]
7.80±0.40(Predicted) |
Hazard Information | Back Directory | [Uses]
Integracin B is a unusual ester and potent inhibitor of HIV-1. | [Uses]
Integracin B is an unusual ester of two structurally related alkylresorcinols first isolated from a fungus, Cytonaema sp., in 2002 as a potent inhibitor of HIV-1 integrase. With the exception of this initial report, integracin B has received little further attention. | [Uses]
Integracin B is an unusual ester of two structurally related alkylresourcinols first isolated from a fungus, Cytonaema sp., in 2002 as a potent inhibitor of HIV-1 integrase. With the exception of this initial report, Integracin B has received little further attention. | [Definition]
ChEBI: Integracin B is a benzoate ester obtained by the formal condensation of the hydroxy group of 5-(8-hydroxyundecyl)benzene-1,3-diol with 4,6-dihydroxy benzoic acid which is also substituted by a 8-hydroxyundecyl group at position 2. It is isolated from Cytonaema sp. and has anti-HIV-1 activity. It has a role as a metabolite and a HIV-1 integrase inhibitor. It is a member of resorcinols, a benzoate ester and a secondary alcohol. | [storage]
Store at -20°C |
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