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ChemicalBook--->CAS DataBase List--->2237268-08-3

2237268-08-3

2237268-08-3 Structure

2237268-08-3 Structure
IdentificationBack Directory
[Name]

SBI-797812
[CAS]

2237268-08-3
[Synonyms]

SBI-797812
Urea, N-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-ylsulfonyl)phenyl]-N'-(4-pyridinylmethyl)-
[Molecular Formula]

C19H22N4O4S
[MOL File]

2237268-08-3.mol
[Molecular Weight]

402.47
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: 2mg/mL, clear
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Biochem/physiol Actions]

SBI-797812 is a cell penetrant and potent activator of nicotinamide phosphoribosyltransferase (NAMPT) that increases intracellular levels of NMN and NAD+ in cells. SBI-797812 blocks binding of inhibitors to NAMPT and shifts the reaction equilibrium towards NMN formation. It elevates levels of NAD+ in mice liver.
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