| Chemical Properties | Back Directory | [Boiling point ]
1160.1±65.0 °C(Predicted) | [density ]
1.314±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO|107.47|100| | [form ]
Solid | [pka]
13.54±0.46(Predicted) | [color ]
Light green to yellow |
| Hazard Information | Back Directory | [Description]
SJF 1521 is a selective EGFR PROTAC?? Degrader based on the EGFR inhibitor lapatinib linked to a von Hippel-Lindau (VHL) recruiting ligand by PEG3. SJF 1521 exhibits selectivity for EGFR, including mutant forms, over HER2 and induces degradation of EGFR in OVCAR8 cells. | [storage]
Store at -20°C |
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