Identification | Back Directory | [Name]
3,4',5-TRIMETHOXY-TRANS-STILBENE | [CAS]
22255-22-7 | [Synonyms]
TriMethoxystibene Trimethoxystilbene TRISMETHOXY RESVERATROL Tri-O-methylresveratrol Resveratrol three ether Trimethoxy-trans-stilbene 3,5,4'-TriMethoxy Stilbene trans-Trimethoxyresveratrol (E)-3,5,4'-Trimethoxystilbene trans-trismethoxy Resveratrol E-Resveratrol TriMethyl Ether B-0022 TrisMethoxyresveratrol (E)-3,4',5-Trimethoxystilbene 3,5,4'-Trimethoxy-trans-stilbene trans-3,4',5-TriMethoxy-stilbene 3,4',5-TRIMETHOXY-TRANS-STILBENE 3,4,5-TRIMETHOXY-TRANS-STILBENE 95+% (E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene 1 (E)-5-[2-(4-HYDROXYPHENYL)ETHENYL]-1,3-BENZENE DIOL 1,3-DIMETHOXY-5-[(E)-2-(4-METHOXY-PHENYL)-VINYL]-BENZENE 1,3-DIMETHOXY-5-[(1E)-2-(4-METHOXYPHENYL)ETHENYL]-BENZENE TRANS-1-(3,5-DIMETHOXYPHENYL)-2-(4-METHOXYPHENYL)ETHYLENE Benzene,1,3-diMethoxy-5-[(1E)-2-(4-Methoxyphenyl)ethenyl]- | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C17H18O3 | [MDL Number]
MFCD02093500 | [MOL File]
22255-22-7.mol | [Molecular Weight]
270.32 |
Chemical Properties | Back Directory | [Appearance]
Pale Yellow Oil | [Melting point ]
57°C | [Boiling point ]
423.8±35.0 °C(Predicted) | [density ]
1.104±0.06 g/cm3(Predicted) | [storage temp. ]
?20°C | [solubility ]
DMSO: ≥34mg/mL | [form ]
powder to crystal | [color ]
white to tan | [CAS DataBase Reference]
22255-22-7 |
Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Oil | [Uses]
A resveratrol analog with a variety of pharmacology action, including anti-cancer properties, anti-allergic activity, estrogenic activity, antiangiogenic activity, and vascular-targeting activity against microtubule-destabilization | [Uses]
A resveratrol analog with a variety of pharmacology action, including
inst microtubule-destabilization | [Uses]
Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. When the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers, the inhibition of cell growth and pro-apoptotic activities of resveratrol are enhanced. | [Description]
trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities.1,2,3,4 It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively).2 trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay.3 It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM.4 | [storage]
Store at -20°C |
|
|