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ChemicalBook--->CAS DataBase List--->2222768-84-3

2222768-84-3

2222768-84-3 Structure

2222768-84-3 Structure
IdentificationBack Directory
[Name]

Dynarrestin
[CAS]

2222768-84-3
[Synonyms]

Dynarrestin
Dynarrestin >=98% (HPLC)
Dynarrestin,Hedgehog,Inhibitor,inhibit
Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate
5-Thiazolecarboxylic acid, 4-[4-(diethylamino)phenyl]-2-[(2,4-difluorophenyl)amino]-, ethyl ester
[Molecular Formula]

C22H23F2N3O2S
[MDL Number]

MFCD32174341
[MOL File]

2222768-84-3.mol
[Molecular Weight]

431.5
Chemical PropertiesBack Directory
[storage temp. ]

4°C, protect from light ,unstable in solution, ready to use.
[solubility ]

Soluble in DMSO
[form ]

A solid
[color ]

Light brown to brown
Hazard InformationBack Directory
[Uses]

Dynarrestin is an dynein inhibitor. Inhibits hedgehog signaling in vitro (IC50 = 0.22 μM). Exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport. Inhibits tumor cell proliferation in a mouse medulloblastoma model.
[storage]

Store at -20°C
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