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ChemicalBook--->CAS DataBase List--->2207596-93-6

2207596-93-6

2207596-93-6 Structure

2207596-93-6 Structure
IdentificationBack Directory
[Name]

MPEG11-CH2CH2COONHS
[CAS]

2207596-93-6
[Synonyms]

MPEG11-CH2CH2COONHS
4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxaoctatriacontanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C30H55NO16
[MDL Number]

MFCD13184970
[MOL File]

2207596-93-6.mol
[Molecular Weight]

685.75
Chemical PropertiesBack Directory
[Boiling point ]

684.3±65.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[form ]

Liquid
[color ]

Colorless to light yellow
[InChIKey]

ZMXRHHJWXLKMTL-UHFFFAOYSA-N
[SMILES]

C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
Hazard InformationBack Directory
[Biological Activity]

m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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