| Identification | Back Directory | [Name]
Canagliflozin-10 | [CAS]
2161394-94-9 | [Synonyms]
Canagliflozin-10
canagliflozin impurities3
canagliflozin impurities613
Canagliflozin Furanose Form (Mixture of Anomers)
D-Galactitol, 1,4-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-
(2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol
Canagliflozin impurity 9/(2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol | [Molecular Formula]
C24H25FO5S | [MDL Number]
MFCD32669800 | [MOL File]
2161394-94-9.mol | [Molecular Weight]
444.52 |
| Chemical Properties | Back Directory | [Melting point ]
>53°C (dec) | [Boiling point ]
673.5±55.0 °C(Predicted) | [density ]
1.375±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Sonicated) | [form ]
Solid | [pka]
13.56±0.70(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic | [InChIKey]
ZLPSHXQANWMHSC-HWVOYRNVNA-N | [SMILES]
O[C@@H]1[C@H]([C@]([H])([C@H](O)CO)OC1C1C=CC(C)=C(CC2=CC=C(C3C=CC(F)=CC=3)S2)C=1)O |&1:1,2,3,5,r| |
| Hazard Information | Back Directory | [Uses]
1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucose is an intermediate used in the synthesis of Canagliflozin (C175190). Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor; Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. |
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| Company Name: |
TOSUN PHARM
|
| Tel: |
020-61855200 13326451905 |
| Website: |
www.toref.cn/ |
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