Identification | Back Directory | [Name]
CALCITONIN, HUMAN | [CAS]
21215-62-3 | [Synonyms]
calcitonin M Unii-I0io929019 Einecs 244-276-2 human C carcinoma CALCITONIN, HUMAN hCT
Thyrocalcitonin CALCITONIN M, HUMAN* THYROCALCITONIN HUMAN Human calcitonin (1-32) Calcitonin, human synthetic 1,7-Dicarbacalcitonin【human】 Calcitonin Human,recombinant Calcitonin,huMan,Calcitonin,hu Calcitonin, human, for bioassay calcitonin m, human c carcinoma Calcitonin, human reduced cyclic(1→7)-disulfide CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-NH2 (DISULFIDE BRIDGE: 1-7) Calcitonin M, human C carcinoma, Calcitonin, human reduced cyclic (1-7)-disulfide, hCT, Thyrocalcitonin CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 CYST-GLY-ASN-LEU-SER-THR-CYST-MET-LEU-GLY-THR-TYR-THR-GLN-AS-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO NH2 H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 HUMAN H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 (DISULFIDE BRIDGE: 1-7) | [EINECS(EC#)]
244-276-2 | [Molecular Formula]
C151H226N40O45S3 | [MDL Number]
MFCD00167520 | [MOL File]
21215-62-3.mol | [Molecular Weight]
3417.85 |
Chemical Properties | Back Directory | [Boiling point ]
3061.8±65.0 °C(Predicted) | [density ]
1.326±0.06 g/cm3(Predicted) | [RTECS ]
XP3560000 | [storage temp. ]
−20°C
| [solubility ]
Soluble in DMSO | [form ]
powder
| [color ]
White to off-white | [Water Solubility ]
Soluble to 2 mg/ml in water | [Merck ]
13,1642 |
Hazard Information | Back Directory | [Uses]
Calcitonin human has been used to study its ability to stimulate cAMP production post transfection in mammalian cell by activating human CALCRL (calcitonin receptor like receptor gene)- receptor activity-modifying protein 1 (RAMP1) and CTR (calcitonin receptor). | [Uses]
Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. A carrier peptide that can be used to internalize fusion proteins | [Uses]
Regulator (calcium). | [Brand name]
Calcimar (Rhone-
Poulenc Rorer);. | [Biochem/physiol Actions]
Calcitonin, also referred to as thyrocalcitonin, is a 32 amino acid peptide hormone, which is present abundantly in seminal plasma compared to serum. It acts as a first messenger and hence regulates the the production of cAMP as well as mammalian sperm function. It also facilitates the regulation of different isoforms of adenylyl cyclase. | [storage]
Store at -20°C |
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