| Identification | Back Directory | [Name]
3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE | [CAS]
21172-41-8 | [Synonyms]
3-(Trifluoromethyl)benzenepropanal
4-[3-(trifluoroMethyl)phenyl]butanal
Benzenepropanal, 3-(trifluoroMethyl)-
3-(3-(trifluoroMethyl)phenyl)propanal
m-(Trifluoromethyl)hydrocinnamaldehyde
3-(trifluoroMethylphenyl)propionaldehyde
3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIOLDEHYDE
3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE | [EINECS(EC#)]
606-717-0 | [Molecular Formula]
C10H9F3O | [MDL Number]
MFCD07772918 | [MOL File]
21172-41-8.mol | [Molecular Weight]
202.17 |
| Chemical Properties | Back Directory | [Appearance]
Colourless Oil | [Boiling point ]
207.4±35.0 °C(Predicted) | [density ]
1.192±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Soluble in Chloroform, Dichloromethane, Ethyl acetate | [form ]
Oil | [color ]
Clear colorless to pale yellow oily liquid | [Stability:]
Not very stable, new spot on TLC if kept at r.t. o/n. | [InChI]
InChI=1S/C10H9F3O/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1,3,5-7H,2,4H2 | [InChIKey]
APCCHYPQHODSBD-UHFFFAOYSA-N | [SMILES]
C1(CCC=O)=CC=CC(C(F)(F)F)=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
Colourless Oil | [Synthesis]
A solution of 3-(Trifluoromethyl) benzene propanol (1.0 g, 4.90 mmol) in dichloromethane (20 ml) is cooled in a water/ice bath, treated in succession with DMSO (770 mg, 9.80 mmol) and P2O5 (1.39 g, 9.80 mmol) and left under stirring for 30 minutes, while temperature raises to 20°C. The reaction mixture is then cooled in water/ice bath and triethylamine (2.4 ml, 17.15 mmol). The resulting solution is kept under stirring while the temperature raises to 20°C. After one hour, the mixture is treated with 5 per cent HCl, the phases are separated, and the organic one is further washed with 5 per cent HCl. The organic phase is then washed with brine, dried over Na2SO4, filtered and concentrated under reduced pressure to afford 0.99 g of the aldehyde of 3-(3-(Trifluoromethyl)phenyl)propanal in quantitative yield. |
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