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ChemicalBook--->CAS DataBase List--->209125-28-0

209125-28-0

209125-28-0 Structure

209125-28-0 Structure
IdentificationBack Directory
[Name]

APHS
[CAS]

209125-28-0
[Synonyms]

APHS
Aids081123
Aids-081123
2-(2-HEPTYNYLTHIO)-PHENOL ACETATE
PHENOL 2-(2-HEPTYNYLTHIO)-ACETATE
o-(Acetophenyl)hept-2-ynyl sulphide
o-(Acetoxyphenyl)hept-2-ynyl sulphide
Phenol, 2-(2-heptyn-1-ylthio)-, 1-acetate
[Molecular Formula]

C15H18O2S
[MDL Number]

MFCD02183594
[MOL File]

209125-28-0.mol
[Molecular Weight]

262.37
Chemical PropertiesBack Directory
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Oil.
[color ]

Clear Colorless to Light Yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H336
[Precautionary statements ]

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Uses]

An O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1.
[Uses]

An O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1.
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