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ChemicalBook--->CAS DataBase List--->2088771-60-0

2088771-60-0

2088771-60-0 Structure

2088771-60-0 Structure
IdentificationBack Directory
[Name]

Sitagliptin Impurity 21
[CAS]

2088771-60-0
[Synonyms]

2088771-60-0
Sitagliptin-14
Sitagliptin FP Impurity A
Sitagliptin Impurity FP-A
USPSitagliptinFumarateadduct
2-(((R)-4-oxo-4-(3-(trifluoromethyl)
Sitagliptin Tablets EP Impurity FP-A
Sitagliptin Fumarate Adduct Impurity
Sitagliptin Fumarate Adduct(Sitagliptin Impurity FP-A)
(R)-Sitagliptin rac-Fumarate Adduct (mixture of diastereomers)
Sitagliptin FP Impurity A/ Sitagliptin Fumarate Adduct/ Sitagliptin Maleate Adduct
((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl) aspartic acid
2-{[(2R)-4-oxo-4-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]amino}butanedioic acid
L-Aspartic acid, N-[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-
Sitagliptin impurity 5/Sitagliptin FP Impurity A/Sitagliptin Fumarate Adduct/Sitagliptin Maleate Adduct/N-[(2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]aspartic acid
[Molecular Formula]

C20H19F6N5O5
[MDL Number]

MFCD33550932
[MOL File]

2088771-60-0.mol
[Molecular Weight]

523.39
Chemical PropertiesBack Directory
[Melting point ]

149 - 153°C
[Boiling point ]

673.9±65.0 °C(Predicted)
[density ]

1.66±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

2.05±0.23(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

Sitagliptin Fumarate Adduct is an impurity of Sitagliptin (S491000), a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
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