| Identification | Back Directory | [Name]
2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl- | [CAS]
2088735-51-5 | [Synonyms]
FLT3-IN-10
2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl- | [Molecular Formula]
C15H11FN2O | [MOL File]
2088735-51-5.mol | [Molecular Weight]
254.26 |
| Chemical Properties | Back Directory | [Boiling point ]
401.3±37.0 °C(Predicted) | [density ]
1.265±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
3.53±0.10(Predicted) | [color ]
Light yellow to light brown |
| Hazard Information | Back Directory | [Biological Activity]
FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 has the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML)[1]. | [References]
[1]. Kim HJ, et al. Discovery of Oxazol-2-amine Derivatives as Potent Novel FLT3 Inhibitors. Molecules. 2020;25(21):5154. |
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