| Identification | Back Directory | [Name]
Acid-PEG1-t-butyl ester | [CAS]
2086689-08-7 | [Synonyms]
COOH-PEG1-OtBu
COOH-PEG1-COOtBu
Acid-PEG1-C2-Boc
Acid-PEG1-t-butyl ester
3-(3-(tert-Butoxy)-3-oxopropoxy)propanoic acid
3-(2-Carboxyethoxy)propanoic acid 1-tert-butyl ester
Propanoic acid, 3-(2-carboxyethoxy)-, 1-(1,1-dimethylethyl) ester | [Molecular Formula]
C10H18O5 | [MDL Number]
MFCD30723273 | [MOL File]
2086689-08-7.mol | [Molecular Weight]
218.25 |
| Chemical Properties | Back Directory | [Boiling point ]
341.9±22.0 °C(Predicted) | [density ]
1.101±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [pka]
4.27±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Acid-PEG1-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. |
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