| Identification | Back Directory | [Name]
BAY-1797 | [CAS]
2055602-83-8 | [Synonyms]
BAY-1797
paw,ion,inhibit,anti-inflammatory,CFA,Complete,P2XRs,BAY-1797,Freund’s,selective,channel,P2X Receptor,inflamed,Inhibitor,BAY1797,Adjuvant,BAY 1797,P2X,anti-nociceptive | [Molecular Formula]
C20H17ClN2O4S | [MOL File]
2055602-83-8.mol | [Molecular Weight]
416.88 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO (>25 mg/ml) | [form ]
solid | [color ]
Pale brown | [Stability:]
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Hazard Information | Back Directory | [Description]
BAY-1797 (2055602-83-8) is a selective P2X4 receptor antagonist (IC50 = 211 nM HEK cellular assay; P2X4 calcium influx based assays – hIC50 = 108 nM, mIC50 = 112 nM, rIC50 = 233 nM).1 Displayed antinociceptive and anti-inflammatory effects in mouse CFA inflammatory pain models. | [storage]
Store at -20°C | [References]
Werner et al. (2019) Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile; J. Med. Chem. 62 11194 |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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cjbscvictory
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13348960310 13348960310 |
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http://www.weikeqi-biotech.com/ |
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