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ChemicalBook--->CAS DataBase List--->195875-69-5

195875-69-5

195875-69-5 Structure

195875-69-5 Structure
IdentificationBack Directory
[Name]

8-Azabicyclo[3.2.1]octane, 3-(3,4-dichlorophenyl)-2-(methoxymethyl)-8-methyl-, (1R,2R,3S,5S)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:)
[CAS]

195875-69-5
[Synonyms]

GSK372475
GSK-372475
GSK 372475
NS-2359 citrate
8-Azabicyclo[3.2.1]octane, 3-(3,4-dichlorophenyl)-2-(methoxymethyl)-8-methyl-, (1R,2R,3S,5S)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:)
[Molecular Formula]

C22H29Cl2NO8
[MOL File]

195875-69-5.mol
[Molecular Weight]

506.37
Hazard InformationBack Directory
[Description]

NS-2359 is a serotonin-norepinephrine-dopamine reuptake inhibitor. It was under development by GlaxoSmithKline (GSK) as an antidepressant, but was discontinued in 2009 when phase II clinical trials turned up disappointing results and did not support further effort by the company. NS-2359 was also in clinical trials for the treatment of ADHD, phase II having been completed in 2007. A trial exploring the effect of NS-2359 on cocaine-experienced individuals is currently ongoing.
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Company Name: TargetMol Chemicals Inc.
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