| Identification | Back Directory | [Name]
4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE | [CAS]
193551-00-7 | [Synonyms]
CAY10398
4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE
Benzamide, 4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]- | [Molecular Formula]
C15H23N3O3 | [MDL Number]
MFCD05863979 | [MOL File]
193551-00-7.mol | [Molecular Weight]
293.36 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:5): 300 μg/ml; DMSO: 14 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 μM. Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. However, trichostatin A is much more expensive than CAY10398. CAY10398 thus represents a selective and cost-effective compound for the inhibition of HDAC. | [Uses]
A histone deacetylase (HDAC1) inhibitor |
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
|
| Tel: |
4008-099-669 |
| Website: |
http://www.is0513.com/ShowSupplierProductsList112975/0.htm |
|