| Identification | Back Directory | [Name]
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE | [CAS]
186689-07-6 | [Synonyms]
2-NBDG
NBD-GLUCOSE
2-NBD-Glucose
2-NBDG min. 95%
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE
D-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-
2-NBDG,2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose >=97% (HPLC)
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose, 90%, mixed Isomers
2-NBDG [2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose] *CAS#: 186689-07-6* | [Molecular Formula]
C12H14N4O8 | [MDL Number]
MFCD03454140 | [MOL File]
186689-07-6.mol | [Molecular Weight]
342.26 |
| Chemical Properties | Back Directory | [Melting point ]
137 - 140°C | [Boiling point ]
740.0±70.0 °C(Predicted) | [density ]
1.750±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
Soluble in DMSO (up to 10 mg/ml). | [form ]
solid | [pka]
12.96±0.20(Predicted) | [color ]
Dark yellow to orange/red | [BRN ]
7603370 | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| Hazard Information | Back Directory | [Description]
2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose (Item No. 23733), but not L-glucose (Item No. 20829) or sucrose, in E. coli.1 It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies.1,2,3,4 2-NBDG displays excitation/emission maxima of 475/550 nm, respectively.1 | [Uses]
2-NBDG is a fluorescent glucose uptake indicator, used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. | [storage]
Store at -20°C | [References]
1) Yoshioka?et al. (1996),?A novel fluorescent derivative of glucose applicable to the assessment of glucose uptake activity of Escherichia coli; Biochim. Biophys. Acta,?1289?5
2) Yamada?et al. (2000),?Measurement of glucose uptake and intracellular calcium concentration in single, living, pancreatic beta-cells; J. Biol. Chem.,?275?22278
3) Loaiza?et al. (2003),?Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy; J. Neurosci.,?23?7337 |
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