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ChemicalBook--->CAS DataBase List--->185106-16-5

185106-16-5

185106-16-5 Structure

185106-16-5 Structure
IdentificationBack Directory
[Name]

AcotiaMide
[CAS]

185106-16-5
[Synonyms]

Acofide
AcotiaMide
ACOTIAMIDUM
185106-16-5
Acotiamide D4
YM443 free base
Z-338 free base
Acotiamide formate salt
N-{2-[bis(1-methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dime...
N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide
N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride
4-Thiazolecarboxamide, N-[2-[bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-
N-{2-[bis(1-methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dimethoxyphenyl)carbonyl]amino}-1,3-thiazole-4-carboxamide
Acotiamide D6Q: What is Acotiamide D6 Q: What is the CAS Number of Acotiamide D6 Q: What is the storage condition of Acotiamide D6 Q: What are the applications of Acotiamide D6
[Molecular Formula]

C21H30N4O5S
[MDL Number]

MFCD00953661
[MOL File]

185106-16-5.mol
[Molecular Weight]

450.552
Chemical PropertiesBack Directory
[density ]

1.246±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

powder
[pka]

7.38±0.50(Predicted)
[color ]

white to beige
[Water Solubility ]

H2O: 20mg/mL, clear
Hazard InformationBack Directory
[Definition]

ChEBI: Acotiamide is a member of salicylamides.
[Biological Activity]

Acotiamide is a potentselective and reversible inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide showed no affinity for dopamine D2 or serotonin 5-HT4 receptors but does have activity as a muscarinic antagonist. It acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonismand has been used for the treatment of functional dyspepsia (FD) involving gastric motility dysfunction.
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