Identification | Back Directory | [Name]
Vildagliptin iMpurity A-F | [CAS]
1846606-32-3 | [Synonyms]
ZA(R)-Isomer Vildagliptin IMP Valdagliptin impurity Vildagliptin Impurity 29 Vildagliptin Impurity 73 Vildagliptin iMpurity A-F (2S)-1-(aminoacetyl)pyrrolidine-2-carbonitrile (8aS)-3-hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-hydroxy-, (8aS)- | [Molecular Formula]
C7H10N2O3 | [MDL Number]
MFCD34179904 | [MOL File]
1846606-32-3.mol | [Molecular Weight]
170.17 |
Hazard Information | Back Directory | [Uses]
3-Hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione is an impurity of Vildagliptin (V305000), part of a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic. |
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