| Identification | Back Directory | [Name]
OSI-420 | [CAS]
183320-51-6 | [Synonyms]
CP-473420
OSI420 HCl
7-(2&rsquo
OSI-420 USP/EP/BP
DesMethyl Erlotinib
OSI-420 hydrochloride
6-O-Desmethyl Erlotinib 2
OSI-420 (DesMethyl Erlotinib)
Desmethyl Erlotinib (OSI-420)
Desmethyl Erlotinib hydrochloride
O-Desmethylerlotinib hydrochloride
DesMethyl Erlotinib (CP-473420) HCl
6-O-Desmethyl Erlotinib Hydrochloride
O-Desmethylerlotinib hydrochloride salt
OSI-420 (DesMethyl Erlotinib,CP-473420)
Erlotinib O-Desmethyl Metabolite Isomer HCl
Erlotinib O-DesMethyl Metabolite IsoMer (M14) HCl
Erlotinib O-Desmethyl Metabolite Isomer (M14) Hydrochloride
DESMETHYL ERLOTINIB; CP-473420; OSI420; OSI 420; CP473420; CP 473420
2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol
OSI420/OSI-420/Desmethyl erlotinib /O-Desmethylerlotinib hydrochloride
2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-o
2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanolhydrochloride
2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride
2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol hydrochloride
Ethanol, 2-[[4-[(3-ethynylphenyl)aMino]-7-(2-Methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride
Ethanol, 2-[[4-[(3-ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride (1:1) | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C21H22ClN3O4 | [MDL Number]
MFCD22420811 | [MOL File]
183320-51-6.mol | [Molecular Weight]
415.87 |
| Hazard Information | Back Directory | [Uses]
OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
| [target]
EGFR | [storage]
Store at -20°C |
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