Identification | Back Directory | [Name]
N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE | [CAS]
18303-04-3 | [Synonyms]
TsNBoc LABOTEST-BB LT00453242 N-Boc-toluenesulfonamide tert-Butyl tosylcarbamate N-BOC-P-TOLUENESULFONAMIDE tert-Butyl N-tosylcarbamate (tert-Butoxycarbonyl)tosylamine tert-Butyl N-(p-tosyl)carbamate N-Boc-4-methylbenzenesulfonamide Tosylcarbamic acid tert-butyl ester N-Tosylcarbamic acid tert-butyl ester N-(tert-Butoxycarbonyl-p-tolunesulfonamide N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE ert-butylN-(4-methylphenyl)sulfonylcarbamate N-Boc-p-toluenesulfonamide, 99%, for synthesis tert-butyl N-(4-methylphenyl)sulfonylcarbamate N-(tert-Butoxycarbonyl)-p-toluenesulfonamide > N-(p-Tolylsulfonyl)carbamic acid tert-butyl ester N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE ISO 9001:2015 REACH N-(tert-Butoxycarbonyl)-p-toluenesulfonamide Carbamic acid,N-[(4-methylphenyl)sulfonyl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C12H17NO4S | [MDL Number]
MFCD00134267 | [MOL File]
18303-04-3.mol | [Molecular Weight]
271.33 |
Chemical Properties | Back Directory | [Melting point ]
121-123 °C(lit.)
| [density ]
1.201±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
chloroform: soluble25mg/mL, clear, colorless | [pka]
4.84±0.10(Predicted) | [InChIKey]
DUTLOVSBVBGNDM-UHFFFAOYSA-N | [CAS DataBase Reference]
18303-04-3 |
Hazard Information | Back Directory | [Uses]
N-(tert-Butoxycarbonyl)-p-toluenesulfonamide may be used in the preparation of enyne amide, precursor for Pauson-Khand reaction. | [Synthesis Reference(s)]
Tetrahedron Letters, 35, p. 379, 1994 DOI: 10.1016/0040-4039(94)85058-5 | [General Description]
N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is a N-substituted sulphonamide and its reaction with N-trityl L-serine esters under Mitsunobu reaction conditions is reported. It can be directly coupled with primary, secondary and allylic alcohols under Mitsunobu conditions to afford various sulfonyl-protected amines. |
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