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ChemicalBook--->CAS DataBase List--->182563-08-2

182563-08-2

182563-08-2 Structure

182563-08-2 Structure
IdentificationBack Directory
[Name]

LY 334370 HYDROCHLORIDE
[CAS]

182563-08-2
[Synonyms]

Y334370
LY 334370
Y 334370 HCL
LY 334370 HCL
LY 334370 HYDROCHLORIDE
LY334370;LY-334370;LY 334370
LY-334370 hydrochloride hydrate
4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benazmide
4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indol-5-yl]-benzamide
BenzaMide, 4-fluoro-N-[3-(1-Methyl-4-piperidinyl)-1H-indol-5-yl]-
4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamidehydrochloride
4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benzamide hydrochloride
4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benazmide hydrochloride
4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide hydrochloride hydrate
[Molecular Formula]

C21H22FN3O
[MDL Number]

MFCD11519957
[MOL File]

182563-08-2.mol
[Molecular Weight]

351.42
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

H2O: ≥5mg/mL (warmed)
[form ]

powder
[color ]

white to tan
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H317-H319
[Precautionary statements ]

P280-P305+P351+P338
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

LY 334370 Hydrochloride is a 5-HT1f receptor agoniist used potentially in the treatment of migranes.
[Biological Activity]

Selective 5-HT 1F receptor agonist (K i values are 1.87, 16.4, > 100 (IC 50 ), 176, 189, 281, 1280, 1530, 1550, > 3000 (IC 50 ) and 3250 nM for 5-HT 1F , 5-HT 1A , 5-HT 4 , 5-HT 1E , 5-HT 1B , 5-HT 1D , 5-HT 2B , 5-HT 2A , 5-HT 7 , 5-HT 6 and 5-HT 2C receptors respectively). Displays antimigraine effects.
[storage]

Store at -20°C
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