| Identification | Back Directory | [Name]
3-keto Sphinganine (d12:0) (hydrochloride) | [CAS]
1823032-02-5 | [Synonyms]
3-keto-C12-Dihydrosphingosine HCl salt
3-keto Sphinganine (d12:0) (hydrochloride) | [Molecular Formula]
C12H26ClNO2 | [MDL Number]
MFCD24672582 | [MOL File]
1823032-02-5.mol | [Molecular Weight]
251.8 |
| Hazard Information | Back Directory | [Description]
3-keto Sphinganine (d12:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0) . 3-keto Sphinganine (d18:0) is a lyso-sphingolipid formed by the condensation of L-serine and palmitoyl-CoA by serine palmitoyl transferase (SPT). Vitamin K deficiency inactivates SPT resulting in a decrease in the production of 3-keto sphinganine and other sphingolipids.1 | [References]
1. Batheja, A.D., Uhlinger, D.J., Carton, J.M., et al. Characterization of serine palmitoyltransferase in normal human tissues J. Histochem. Cytochem. 51(5),687-696(2003). |
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