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ChemicalBook--->CAS DataBase List--->1807530-10-4

1807530-10-4

1807530-10-4 Structure

1807530-10-4 Structure
IdentificationBack Directory
[Name]

Azido-PEG3-aldehyde
[CAS]

1807530-10-4
[Synonyms]

N3-PEG3-ALD
N3-PEG3-CHO
N3-PEG3-CH2CH2CHO
Azido-PEG3-aldehyde
[Molecular Formula]

C9H17N3O4
[MDL Number]

MFCD28976706
[MOL File]

1807530-10-4.mol
[Molecular Weight]

231.25
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to off-white
Hazard InformationBack Directory
[Biological Activity]

Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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