Identification | Back Directory | [Name]
JFPVXVDWJQMJEE-QDGUUNGESA-N | [CAS]
1803240-98-3 | [Synonyms]
JFPVXVDWJQMJEE-QDGUUNGESA-N Cefuroxime D3Q: What is
Cefuroxime D3 Q: What is the CAS Number of
Cefuroxime D3 Q: What is the storage condition of
Cefuroxime D3 Q: What are the applications of
Cefuroxime D3 | [Molecular Formula]
C16H16N4O8S | [MOL File]
1803240-98-3.mol | [Molecular Weight]
424.38 |
Hazard Information | Back Directory | [Description]
Cefuroxime-d3 is intended for use as an internal standard for the quantification of cefuroxime by GC- or LC-MS. Cefuroxime is a cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria including S. pyogenes, S. pneumoniae, S. viridans, E. coli, P. mirabilis, H. influenzae, and N. gonorrhoeae (mean MICs = 0.005-8.2 μg/ml). Like other cephalosporins, cefuroxime inhibits peptidoglycan crosslinking and bacterial cell wall synthesis. It is resistant to hydrolysis by bacterial β-lactamases, increasing its efficacy against β-lactamase-producing Gram-negative bacteria. Cefuroxime is protective against Gram-positive and Gram-negative infections in vivo with mean ED50 values ranging from 2 to 35 and 1 to 55 mg/kg, in mice and rats, respectively. Formulations containing cefuroxime have been used to treat urinary tract infections. | [storage]
Store at -20°C |
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