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ChemicalBook--->CAS DataBase List--->1800487-55-1

1800487-55-1

1800487-55-1 Structure

1800487-55-1 Structure
IdentificationBack Directory
[Name]

OT-82
[CAS]

1800487-55-1
[Synonyms]

OT-82
[Molecular Formula]

C26H21FN4O
[MDL Number]

MFCD32708530
[MOL File]

1800487-55-1.mol
[Molecular Weight]

424.47
Chemical PropertiesBack Directory
[Boiling point ]

670.3±55.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

14.46±0.46(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Description]

OT-82 is a potent NAMPT Inhibitor that targets the strong dependence of hematological malignancies on NAD biosynthesis. OT-82 showed strong efficacy against hematopoietic malignancies including acute myeloblastic and lymphoblastic adult and pediatric leukemias, erythroleukemia, multiple myeloma, and Burkitt's lymphoma in vitro and in mouse xenograft models.
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