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ChemicalBook--->CAS DataBase List--->1792999-26-8

1792999-26-8

1792999-26-8 Structure

1792999-26-8 Structure
IdentificationBack Directory
[Name]

NCB-0846
[CAS]

1792999-26-8
[Synonyms]

NCB-0846
[Molecular Formula]

C21H21N5O2
[MDL Number]

MFCD30749187
[MOL File]

1792999-26-8.mol
[Molecular Weight]

375.42
Chemical PropertiesBack Directory
[Boiling point ]

726.2±70.0 °C(Predicted)
[density ]

1.415±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

12.87±0.30(Predicted)
[color ]

Off-White to Light Yellow
[CAS DataBase Reference]

1792999-26-8
Hazard InformationBack Directory
[Uses]

cis-4-?[[2-?(1H-?Benzimidazol-?6-?ylamino)?-?8-?quinazolinyl]?oxy]?-?cyclohexanol inhibits Traf2 and Nck-interacting protein kinase (TNIK). TNIK is involved with Canonical Wnt/b-catenin signalling, which has regulatory roles in maintaining intestinal stem cells and aberration in this pathway has been implicated in colorectal carcinogenesis. TNIK is a therapeutic target.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

NCB-0846(1792999-26-8)1HNMR
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