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ChemicalBook--->CAS DataBase List--->174709-30-9

174709-30-9

174709-30-9 Structure

174709-30-9 Structure
IdentificationBack Directory
[Name]

BPIQ-I
[CAS]

174709-30-9
[Synonyms]

BPIQ-I
N-(3-bromophenyl)-3-methylimidazo[4,5-g]quinazolin-8-amine
8-[(3-BROMOPHENYL)AMINO]-3-METHYL-3H-IMIDAZO[4,5-G]-QUINAZOLINE
8-[(3-BROMOPHENYL)AMINO]-3-METHYL-3H-IMIDAZO[4,5-GAMMA]-QUINAZOLINE
[Molecular Formula]

C16H12BrN5
[MDL Number]

MFCD02179191
[MOL File]

174709-30-9.mol
[Molecular Weight]

354.2
Chemical PropertiesBack Directory
[Boiling point ]

535.5±60.0 °C(Predicted)
[density ]

1.62±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
[form ]

A crystalline solid
[pka]

5.12±0.50(Predicted)
Hazard InformationBack Directory
[Description]

BPIQ-I is a quinazoline that inhibits the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 0.025 nM). It can inhibit the growth of SKOV3 and MDA-468 tumor cell lines with EC50 values of 6.5 and 30 μM, respectively.
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