Identification | Back Directory | [Name]
Cyclophosphamide-d4 | [CAS]
173547-45-0 | [Synonyms]
Cytoxan-d4 Endoxan-d4 Genoxal-d4 Mitoxan-d4 Hexadrin-d4 NSC 26271-d NSC 26271-d4 Cyclostin-d4 Cycloblastin-d4 Cyclophosphamide-d4 N,N-Bis(2-chloroethyl)tetrahydro-4,5-d2-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide | [EINECS(EC#)]
244-379-2 | [Molecular Formula]
C7H15Cl2N2O2P | [MDL Number]
MFCD00144030 | [MOL File]
173547-45-0.mol | [Molecular Weight]
261.086 |
Chemical Properties | Back Directory | [Appearance]
White to Off-White Solid | [Melting point ]
41-450C | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform: Slightly Soluble,Methanol: Slightly Soluble | [form ]
A solid | [color ]
White to off-white |
Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen. | [Description]
Cyclophosphamide-d4 contains four deuterium atoms. It is intended for use as an internal standard for the quantification of cyclophosphamide by GC- or LC-MS. Cyclophosphamide is a nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders. In cells with low levels of aldehyde dehydrogenase, cyclophosphamide acts as a prodrug and is metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death. |
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guoyungurui
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