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ChemicalBook--->CAS DataBase List--->169505-93-5

169505-93-5

169505-93-5 Structure

169505-93-5 Structure
IdentificationBack Directory
[Name]

(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
[CAS]

169505-93-5
[Synonyms]

RS-17053
RS17053HCl
RS 17053 HYDROCHLORIDE
RS 17053 hydrochloride (RS-17053)
RS 17053 hydrochloride (Synonyms: RS-17053)
(N-[2-(2-Cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine)hydrochloride
(N-(2-(2-Cyclopropylmethoxyphenoxy)ethyl)-5-chloro-(a,a)-dimethyl-(1H)-indole-3-ethanamine)hydrochloride
(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
[Molecular Formula]

C24H30Cl2N2O2
[MDL Number]

MFCD01074787
[MOL File]

169505-93-5.mol
[Molecular Weight]

449.41
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

insoluble in ethanol; <22.47mg/ml in DMSO
[form ]

solid
[color ]

White
Hazard InformationBack Directory
[Uses]

RS 17053 Hydrochloride is a selective a1A adrenoceptor antagonist.
[Biological Activity]

α 1A -adrenoceptor antagonist, with very high affinity for α 1A receptors (pK i and pA 2 estimates of 9.1-9.9) and a 30-100 fold selectivity over the α 1B and α 1D subtypes (pK i and pA 2 estimates 7.7-7.8).
[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE(169505-93-5)1HNMR
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