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ChemicalBook--->CAS DataBase List--->16899-81-3

16899-81-3

16899-81-3 Structure

16899-81-3 Structure
IdentificationBack Directory
[Name]

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
[CAS]

16899-81-3
[Synonyms]

U 12844A
Isoprenaline impurity A
Norepinephrine Impurity 10
Isoprenaline EP Impurity A
Isoprenaline impurity A CRS
Isoprenaline EP Impurity A HCl
Isoprenaline HCl EP Impurity A HCl
Isoprenaline hydrochloride EP Impurity A
3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
[2-(3,4-DIHYDROXYPHENYL)-2-OXOETHYL]-PROPAN-2-YLAZANIUM,CHLORIDE
1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone hydrochloride
Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-, hydrochloride (1:1)
[EINECS(EC#)]

240-943-7
[Molecular Formula]

C11H15NO3.ClH
[MDL Number]

MFCD00035076
[MOL File]

16899-81-3.mol
[Molecular Weight]

245.704
Chemical PropertiesBack Directory
[Melting point ]

255-257℃
[storage temp. ]

2-8°C
[form ]

neat
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P301+P312+P330
Hazard InformationBack Directory
[Uses]

1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone is an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia.
[Preparation]

Obtained by condensation of a-chloro-3,4- dihydroxy-acetophenone with isopropylamine in isopropanol at 65–70°. The amino ketone which separated was treated with concentrated hydrochloric acid (54%), (46%).
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