| Identification | Back Directory | [Name]
Micafungin FR-179642 impurity (acid) | [CAS]
168110-44-9 | [Synonyms]
FRAN
FR-179642
MFA/CBR03-2
FR179642, CMICA
FR 179642 (~90%)
Micafungin Nucleus
Micafungin FR-179642
N-1 Micafungin Sodium
Micafungin Impurity 10
Micafungin FR-179642 IMpurity
Micafungin Impurity FR-179642
Micafungin Sodium N-1 intermediate
Micafungin FR-179642 impurity (acid)
1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0
Pneumocandin A0, 1-[(4R,5R)-4,5-dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]- | [Molecular Formula]
C35H52N8O20S | [MDL Number]
MFCD30478434 | [MOL File]
168110-44-9.mol | [Molecular Weight]
936.89 |
| Chemical Properties | Back Directory | [Melting point ]
>150oC (dec.) | [density ]
1.75±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
-4.46±0.18(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
FR 179642 is an impurity of Micafungin (M342350), a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. | [Definition]
Micafungin FR-179642 impurity (acid) is an impurity in micafungin that can be present as trace amounts in the final product and may contribute to hemolytic activity. This impurity is formed by hydrolysis during the synthesis process. Micafungin is an antifungal drug that inhibits the synthesis of ergosterol, a vital component of fungal cell membranes. |
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