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ChemicalBook--->CAS DataBase List--->1679-76-1

1679-76-1

1679-76-1 Structure

1679-76-1 Structure
IdentificationBack Directory
[Name]

Drofenine
[CAS]

1679-76-1
[Synonyms]

Adiphenine H
Trasentin-6H
Cycloadiphene
AGJBLWCLQCKRJP-UHFFFAOYSA-N
2-(DiethylaMino)ethyl 2-cyclohexyl-2-phenylacetate
α-Cyclohexylbenzeneacetic acid 2-(diethylamino)ethyl ester
Benzeneacetic acid, α-cyclohexyl-, 2-(diethylamino)ethyl ester
[Molecular Formula]

C20H31NO2
[MDL Number]

MFCD00865235
[MOL File]

1679-76-1.mol
[Molecular Weight]

317.47
Chemical PropertiesBack Directory
[Boiling point ]

bp0.15 158°
[density ]

1.0047 g/cm3
[pka]

9.21±0.25(Predicted)
Hazard InformationBack Directory
[Originator]

Trasentine A,Ciba
[Definition]

ChEBI: 2-cyclohexyl-2-phenylacetic acid 2-(diethylamino)ethyl ester is a member of benzenes.
[Manufacturing Process]

17.4 parts of diphenylacetic acid 2-(diethylamino)ethyl ester were solved in 200 parts of acetic acid and hydrogenated over platinum catalyst. After the calculated volume of hydrogen was passed, the catalyst was filtered off and the solvent was removed to dryness. Ether, water and a potassium carbonate solution were added to the remaining oil and were thoroughly shaken. The ether layer was washed with water and dried over potassium carbonate. The solvent was removed, the remaining oil was distilled in vacuum to give 2- (diethylamino)ethyl α-phenylcyclohexaneacetate; BP 150°-160°C/0.2 mm Hg.
In practice it is usually used as hydrochloride.
[Therapeutic Function]

Spasmolytic
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