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ChemicalBook--->CAS DataBase List--->166981-13-1

166981-13-1

166981-13-1 Structure

166981-13-1 Structure
IdentificationBack Directory
[Name]

1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl-
[CAS]

166981-13-1
[Synonyms]

1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl-
[Molecular Formula]

C30H55N5O3
[MDL Number]

MFCD00934141
[MOL File]

166981-13-1.mol
[Molecular Weight]

533.79
Chemical PropertiesBack Directory
[Boiling point ]

691.4±53.0 °C(Predicted)
[density ]

1.09±0.1 g/cm3(Predicted)
[storage temp. ]

-20°
[solubility ]

Soluble in DMSO (up to 25 mg/ml)
[form ]

solid
[pka]

14.83±0.20(Predicted)
[color ]

White
[Stability:]

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Hazard InformationBack Directory
[Description]

CT-2584 (166981-13-1; free base) is a cytotoxic agent that alters phospholipid biosynthesis via inhibition of CTP:choline-phosphate cytidylyltransferase causing an increase in phosphatidylinositol with decreasing levels of phosphatidylcholine.1?The altered phospholipid metabolism caused by CT-2584 results in a loss of lamellar structure and membrane integrity (especially in mitochondria and endoplasmic reticulum). CT-2584 was active against a wide range of tumor cell lines including multi-drug resistant lines.2
[References]

1) Finney?et al. (2000),?Pharmacological Inhibition of Phosphatidylcholine Biosynthesis is Associated with Induction of Phosphatidylinositol Accumulation and Cytolysis of Neoplastic Cell lines; Cancer Res.,?60?5204 2) Cheeseman?et al. (2000),?Phase I and pharmacologic study of CT-2584 HMS, a modulator of phosphatidic acid, in adult patients with solid tumors; Br. J. Cancer,?83?1599
166981-13-1 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Tags:166981-13-1 Related Product Information
7689-03-4 2799-07-7 149647-78-9 341031-54-7

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