| Identification | Back Directory | [Name]
CRT-0105950
(CRT0105950) | [CAS]
1661845-86-8 | [Synonyms]
CRT-0105950
(CRT0105950)
4-[[5-[3-(2-Chloro-4-methylphenyl)-4-pyridinyl]-2-thiazolyl]amino]phenol | [Molecular Formula]
C21H16ClN3OS | [MDL Number]
MFCD31689246 | [MOL File]
1661845-86-8.mol | [Molecular Weight]
393.89 |
| Chemical Properties | Back Directory | [Boiling point ]
556.6±60.0 °C(Predicted) | [density ]
1.364±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
10.13±0.26(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
CRT-0105950 is a potent LIMK1/2 inhibitor (IC50 values are 0.3 and 1 nM at LIMK 1 and 2, respectively). Disrupts microtubule organization, inhibits cofilin phosphorylation and increases α-tubulin acetylation in vitro. | [storage]
Store at -20°C |
|
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|