Identification | Back Directory | [Name]
(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile | [CAS]
1640971-60-3 | [Synonyms]
PF-05579970 Tofatib reference ofacitinib iMpurity tofacitinib iMpurity Tofaimpurity iMpurity Tofacitinib Impurity 9 Tofacitinib Impurity 11 Tofacitinib Impurity 14 Tofacitinib Impurity 15 Tofacitinib Impurity 18 Tofacitinib Impurity 21 Tofacitinib Impurity TBA Tofacitinib Impurity TAB Tofacitinib Impurity 5 DiHCl Tofacitinib Citrate Impurity Tofacitinib Related Compound 11 (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile 1-Piperidinepropanenitrile, 3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-, (3R,4R)- N2,N4-bis((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N2,N4-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine 3-((3R,4R)-4-methyl-3-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile butyl (E)-3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate 3-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl) (methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate-one | [Molecular Formula]
C14H20N6O | [MDL Number]
MFCD34179900 | [MOL File]
1640971-60-3.mol | [Molecular Weight]
288.35 |
Chemical Properties | Back Directory | [Melting point ]
238 - 240°C | [Boiling point ]
551.0±50.0 °C(Predicted) | [density ]
1.249±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
6.06±0.60(Predicted) | [color ]
White to Off-White |
Hazard Information | Back Directory | [Uses]
Tofacitinib Citrate Impurity is derived from (3R,?4R)?-N,?4-?Dimethyl-?1-?benzyl?-3-?piperidinamine (D464895), which is a reagent used in the preparation of Janus tyrosine kinase inhibitors for the treatment of autoimmune diseases. |
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Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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