| Identification | Back Directory | [Name]
GPR120 agonist 4x | [CAS]
1628448-77-0 | [Synonyms]
GPR120 Agonist 1
GPR120 agonist 4x
GPR120 Agonist 1,GPR-120 Agonist 1
Benzenepropanoic acid, 4-[[3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)-4-isothiazolyl]methoxy]-3,5-difluoro- | [Molecular Formula]
C20H12ClF6NO3S | [MDL Number]
MFCD32174261 | [MOL File]
1628448-77-0.mol | [Molecular Weight]
495.82 |
| Hazard Information | Back Directory | [Description]
GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1].
GPR120[1] GPR120 Agonist 1 is a potent and selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human GPR120 and mouse GPR120 (the calcium flux assay), respectively[1]. | [storage]
Store at -20°C | [References]
[1]. Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952. |
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cjbscvictory
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13348960310 13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
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