Identification | Back Directory | [Name]
ANTALARMIN HYDROCHLORIDE | [CAS]
157284-96-3 | [Synonyms]
Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)- | [Molecular Formula]
C24H34N4 | [MDL Number]
MFCD00930939 | [MOL File]
157284-96-3.mol | [Molecular Weight]
378.55 |
Chemical Properties | Back Directory | [Boiling point ]
437.2±45.0 °C(Predicted) | [density ]
1.05±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMSO: ~24 mg/mL, soluble
| [form ]
solid
| [pka]
7.10±0.30(Predicted) | [color ]
off-white
|
Hazard Information | Back Directory | [Definition]
ChEBI: Antalarmin is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidin-4-amine which is substituted by methyl groups at positions 2, 5, and 6, by a mesityl group at position 7, and in which the amino substituent at position 4 has been substituted by ethyl and butyl groups. It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors (Ki = 1 nM). It has a role as a corticotropin-releasing factor receptor antagonist. It is a pyrrolopyrimidine and a tertiary amino compound. |
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Company Name: |
SIGMA-RBI
|
Tel: |
800 736 3690 (Orders) |
Website: |
www.sigma-aldrich.com |
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