| Identification | Back Directory | [Name]
DEPMPO | [CAS]
157230-67-6 | [Synonyms]
DEPMPO
5-(Diethoxyphosphoryl)-
5-(DIETHYLPHOSPHONO)-5-METHYL-1-PYRROLINE N-OXIDE
5-(DIETHOXYPHOSPHONYL)-5-METHYL-1-PYRROLINE-N-OXIDE
5-(DIETHOXYPHOSPHORYL)-5-METHYL-1-PYRROLINE-N-OXIDE
5-(Diethylphosphono)-5-methyl-1-pyrroline N-Oxide
2-DIETHYLPHOSPHONO-2-METHYL-3,4-DIHYDRO-2H-PYRROLE 1-OXIDE
(2-METHYL-3,4-DIHYDRO-1-OXIDE-2H-PYRROL-2-YL)DIETHYLPHOSPHONATE
(3,4-Dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-phosphonic acid diethyl ester
P-(3,4-Dihydro-2-Methyl-1-oxido-2H-pyrrol-2-yl)phosphonic Acid Diethyl Ester | [Molecular Formula]
C9H18NO4P | [MDL Number]
MFCD01074976 | [MOL File]
157230-67-6.mol | [Molecular Weight]
235.22 |
| Chemical Properties | Back Directory | [Appearance]
Pale Yellow Oil | [Boiling point ]
412.4±34.0 °C(Predicted) | [density ]
1.14±0.1 g/cm3(Predicted) | [storage temp. ]
Freezer | [solubility ]
Soluble in Water or Ethanol. | [form ]
Colorless to light yellow oil. | [pka]
1.74±0.40(Predicted) | [color ]
Pale yellow | [Stability:]
Hygroscopic Oil, Light Sensitive |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Oil | [Uses]
A spin trap useful as a probe for free radical formation during myocardial ischemia/reperfusion injury. An analogue of DMPO | [Description]
DEPMPO (157230-67-6) is a spin trap capable of detecting oxygen, nitrogen, sulfur and carbon-centered free radicals both in vitro and in vivo. DEPMPO is useful for distinguishing between superoxide-dependent pathways of hydroxyl radical generation, and those that are superoxide independent. | [storage]
Store at -80°C,protect from light | [References]
1) Liu et al. (1999), Evaluation of DEPMPO as a spin trapping agent in biological systems; Free Radic. Biol. Med., 26 714
2) Shi et al. (2005), Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species; Arch. Biochem. Biophys., 437 59
3) Culcasi et al. (2012), EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: evidence for NADPH oxidase and mitochondrial stimulation; Chem. Biol. Interact., 199 161
4) Tampieri et al. (2019), Comment on “Water Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos; ACS Sens. E-pub. Ahead of Print [Focus Citation] |
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| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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